The effect of oxygen on dynamic cerebral autoregulation: critical role of hypocapnia

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The effect of oxygen on dynamic cerebral autoregulation: critical role of hypocapnia.

Hypoxia is known to impair cerebral autoregulation (CA). Previous studies indicate that CA is profoundly affected by cerebrovascular tone, which is largely determined by the partial pressure of arterial O(2) and CO(2). However, hypoxic-induced hyperventilation via respiratory chemoreflex activation causes hypocapnia, which may influence CA independent of partial pressure of arterial O(2). To id...

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2010

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.01235.2009